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The weekend sees the initial Wear-Tyne derby after 2024, but who will emerge victorious – Sunderland or the Magpies?
"For most of last season, you couldn't have imagined the Wearside club rising to the top flight and holding their own with Eddie Howe's Newcastle, never mind being above them in the table," remarked analyst Chris Sutton.
"Things are very different now, and the way Sunderland play leads me to believe they've got a genuine opportunity."
He is offering scoreline guesses for all 380 Premier League games this campaign, in competition with AI, the public and a range of guests.
For this weekend's fixtures, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's formal esports team – at the football simulation European esports championship finals tournament, which is being held at Twickenham Stadium on Saturday.
The action will be streamed on Uefa's YouTube, Instagram Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
What are your thoughts with their predictions? Share your own guesses below.
The most commonly selected scoreline selected for each game is featured in the scoreboards at the bottom of this page.
Getting the win/draw/loss right (picking a win, draw or defeat) is worth 10 points. The exact score earns 40 points.
Ray, who competes for his club side and Manchester City as well as England, is competing for the first time at the eEuros finals after successfully navigating the qualifying.
The final eight competitors will fly the flag at the finals in a single-elimination, competing for a $100,000 prize pool and a prestigious spot in the world finals play-offs, with the Danish representative Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray stated. "There's a really good coach with me and preparation has been going well.
"Representing your country is always an honour to play for your country. Obviously when you are younger, you imagine doing it as an real-life footballer, but when you enter this profession and there is an opportunity to represent England, putting the shirt on is something unique.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"For me he is the best player in the world so getting a win over him in a tournament like this just provides a crazy boost of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were outstanding against Arsenal at the end of November, when they secured a point after going down to 10 men, and many thought they've turned a corner, they could possibly be challengers for the crown.
However, since that game, however, they were beaten physically by Leeds, looked flat against Bournemouth and this week got defeated by Atalanta in the Champions League.
So head coach Enzo Maresca is in need of a win here to get back on track, but it won't be easy because the Toffees are such a threatening team.
Their key midfielders are playing really well and they have got a bit of momentum at the moment.
Current evidence suggests you would likely back Everton, while the most prudent prediction would probably be a draw, but I'm throwing caution to the wind.
The Blues have failed to given me any good cause to back them recently, but I just have a feeling Chelsea will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be fascinating to see what we get from the Reds.
I am really pleased for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the discussion with Mohamed Salah this week.
Slot ought not to put up with that drama. I know Salah has been a great for Liverpool but essentially Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their shape against Inter and went with a midfield diamond formation and two up top.
All the talk is going to be talking about whether Salah is back for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's focus will be on winning this game, but it is a difficult fixture.
It's fair to say it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are vulnerable at the back too.
Liverpool need to get back to winning consistently, but I am not sure how much their exertions at the San Siro will have affected their stamina.
I put a couple of Brighton players in my FPL team, so they will likely do poorly - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to work so hard against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
Apart from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, particularly straight after they've played in the Champions League.
I am expecting that pattern to continue on Sunday, and their lack of freshness is likely to be a key element in how this game goes because of their rivals' intensity.
We saw how incessant Regis le Bris's side are. They bullied the Gunners, and it was amazing to watch.
Commentators talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been superb, but Noah Sadiki, who plays alongside him, has also been one of the top transfers and should be recognised too.
All signs point to this being the best game|most exciting fixture